លេខ Acarbose Cas: 56180-94-0 រូបមន្តម៉ូលេគុល: C25H43NO18
Precos
បុព្វបទ
Prandase
អាកាបូស
គ្លូកូបៃ
bay-g5421
អាស្កាបូស
Acarbose API
អាកាបូស ៩៨%
អាកាបូសអ៊ីដ្រាត
Bay g 5421: Glucobay
អាកាបូស (Acarbosum)
4)-OaD-glucopyranosyl-(1®
-alpha-d-glucopyranosyl-(1-4)-
AMylostatin J, Bay g 5421, alpha-GHI
(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-
Acarbose fom Actinoplanes sp ។ប្រហែល100 FIP-AIU/mg
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHY
d-គ្លុយកូស, o-4,6-dideoxy-4-(((1s-(1-alpha,4-alpha,5-beta,6-alpha))-4,5,6-trihyd
roxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-d-glucopyranosyl-(1-4)-o
4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
D-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -aD-glucopyranosyl-(1®
O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D -glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-គ្លុយកូស
4-O-[4-O-[4-[(1S,4R,5S,6S)-4,5,6-Trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-4 ,6-dideoxy-α-D-glucopyranosyl]-α-D-glucopyranosyl]-D-glucopyranose
D-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glucopyranosyl-(1-4)-OaD-glucopyranosyl-(1-4)-D-glucose
O-4,6-Dideoxy-4-[[[1S(1α,4α,5β,6α-)-4,5,6-trihydrDxy-3-(hydroxymethyl)-2-cyclohexen-1-y1]amino]- α-D-glucopyranosyl-(1→4)-O-α-D-ducopyranosyl-(1→4)-D-glucose
O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glucose
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5b,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glucopyranosyl-(1-4)-OaD-glucopyranosyl-(1-4)-D-gluco-
se
D-Glucose, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1 → 4)-O-α-D-glucopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]AMINO] អាល់ហ្វា-ឌី-គ្លូកូពីរ៉ាណូស៊ីល-(១-៤)-អូ-អាល់ហ្វា-ឌី-គ្លូកូពីរ៉ាណូស៊ីល-(១-៤)-ឌី-គ្លុយកូស
5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL] OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
ចំណុចរលាយ | ១៦៥-១៧០ អង្សាសេ |
ដង់ស៊ីតេ | 1.4278 (ការប៉ាន់ស្មានរដុប) |
សីតុណ្ហភាពផ្ទុក | បរិយាកាសអសកម្ម សីតុណ្ហភាពបន្ទប់ 2-8°C |
ភាពរលាយ | រលាយក្នុងទឹកខ្លាំង រលាយក្នុងមេតាណុល មិនរលាយក្នុង methylene chloride ។ |
សកម្មភាពអុបទិក | គ្មាន |
រូបរាង | ពណ៌ស រឹង |
ភាពបរិសុទ្ធ | ≥97% |
Acarbose ដែលជា oligosaccharide ស្មុគស្មាញដែលដាច់ឆ្ងាយពី Actinoplanes ត្រូវបានគេរាយការណ៍ថាមានប្រយោជន៍ជាការព្យាបាលបន្ថែមចំពោះជំងឺទឹកនោមផ្អែម។ដោយការរារាំង alpha-glucosidase, acarbose ពន្យារការរំលាយអាហារកាបូអ៊ីដ្រាតនៅក្នុងក្រពះពោះវៀន និងកែប្រែការផ្លាស់ប្តូរកម្រិតជាតិស្ករក្នុងឈាមដែលបណ្ដាលមកពីអាហារ។
Acarbose គឺជា pseudo-oligosaccharide ជាមួយនឹងស្ថានីយ C7-cyclitol ដែលត្រូវបានប៉ាតង់នៅឆ្នាំ 1975 ដោយក្រុមហ៊ុន Bayer ។Acarbose គឺជាសមាសធាតុនៃស្មុគស្មាញ amylostatin ដែលផលិតដោយប្រភេទ Actinoplanes និង Streptomyces ។Acarbose ដើរតួជាអ្នករារាំងដ៏ខ្លាំងក្លានៃ α-glucosidases និង saccharases ។ចាប់តាំងពីឆ្នាំ 1990 មក សារធាតុ acarbose ត្រូវបានគេប្រើប្រាស់សម្រាប់ព្យាបាលជំងឺទឹកនោមផ្អែមប្រភេទទី 2 ។
សួរគ្រូពេទ្យជាមុនសិន